Sleep Drives Metabolite Clearance from the Adult Brain

The conservation of sleep across all animal species suggests that sleep serves a vital function. We here report that sleep has a critical function in ensuring metabolic homeostasis. Using real-time assessments of tetramethylammonium diffusion and two-photon imaging in live mice, we show that natural...

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Detalhes bibliográficos
Main Authors: Xie, Lulu, Kang, Hongyi, Xu, Qiwu, Chen, Michael J., Liao, Yonghong, Thiyagarajan, Meenakshisundaram, O’Donnell, John, Christensen, Daniel J., Nicholson, Charles, Iliff, Jeffrey J., Takano, Takahiro, Deane, Rashid, Nedergaard, Maiken
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880190/
https://ncbi.nlm.nih.gov/pubmed/24136970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1241224
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