A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β

Because it lacks a lymphatic circulation, the brain must clear extracellular proteins by an alternative mechanism. The cerebrospinal fluid (CSF) functions as a sink for brain extracellular solutes, but it is not clear how solutes from the brain interstitium move from the parenchyma to the CSF. We de...

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Detalhes bibliográficos
Principais autores: Iliff, Jeffrey J., Wang, Minghuan, Liao, Yonghong, Plogg, Benjamin A., Peng, Weiguo, Gundersen, Georg A., Benveniste, Helene, Vates, G. Edward, Deane, Rashid, Goldman, Steven A., Nagelhus, Erlend A., Nedergaard, Maiken
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551275/
https://ncbi.nlm.nih.gov/pubmed/22896675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3003748
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