NPM-ALK signals through glycogen synthase kinase 3β to promote oncogenesis

Anaplastic large cell lymphoma (ALCL) is the most common type of pediatric peripheral T-cell lymphoma. In 70–80% of cases, the chromosomal aberration t(2;5)(p23;q35) results in the juxtaposition of anaplastic lymphoma kinase (ALK) with nucleophosmin (NPM) and the subsequent expression of the NPM-ALK...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: McDonnell, SRP, Hwang, SR, Basrur, V, Conlon, KP, Fermin, D, Wey, E, Murga-Zamalloa, C, Zeng, Z, Zu, Y, Elenitoba-Johnson, KSJ, Lim, MS
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244868/
https://ncbi.nlm.nih.gov/pubmed/22179823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.542
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