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Effect of glycogen synthase kinase-3 inactivation on mouse mammary gland development and oncogenesis

Many components of the Wnt/β-catenin signaling pathway have critical functions in mammary gland development and tumor formation, yet the contribution of glycogen synthase kinase-3 (GSK-3α and GSK-3β) to mammopoiesis and oncogenesis is unclear. Here, we report that WAP-Cre-mediated deletion of GSK-3...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Dembowy, J, Adissu, H A, Liu, J C, Zacksenhaus, E, Woodgett, J R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490903/
https://ncbi.nlm.nih.gov/pubmed/25195860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.279
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