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NPM-ALK signals through glycogen synthase kinase 3β to promote oncogenesis
Anaplastic large cell lymphoma (ALCL) is the most common type of pediatric peripheral T-cell lymphoma. In 70–80% of cases, the chromosomal aberration t(2;5)(p23;q35) results in the juxtaposition of anaplastic lymphoma kinase (ALK) with nucleophosmin (NPM) and the subsequent expression of the NPM-ALK...
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| Veröffentlicht in: | Oncogene |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4244868/ https://ncbi.nlm.nih.gov/pubmed/22179823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.542 |
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