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Effect of Osmolytes on the Binding of EGR1 Transcription Factor to DNA

Osmolytes play a key role in maintaining protein stability and mediating macromolecular interactions within the intracellular environment of the cell. Herein, we show that osmolytes such as glycerol, sucrose and PEG400 mitigate the binding of EGR1 transcription factor to DNA in a differential manner...

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Detalhes bibliográficos
Publicado no:Biopolymers
Main Authors: Mikles, David C., Bhat, Vikas, Schuchardt, Brett J., McDonald, Caleb B., Farooq, Amjad
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244260/
https://ncbi.nlm.nih.gov/pubmed/25269753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.22556
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