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Enthalpic Factors Override the Polyelectrolyte Effect in the Binding of EGR1 Transcription Factor to DNA
Protein-DNA interactions are highly dependent upon salt such that the binding affinity precipitously decreases with increasing salt concentration in a phenomenon termed the polyelectrolyte effect. In this study, we provide evidence that the binding of EGR1 transcription factor to DNA displays virtua...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3896865/ https://ncbi.nlm.nih.gov/pubmed/24436125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmr.2336 |
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