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Improvement of Dscam homophilic binding affinity throughout Drosophila evolution

BACKGROUND: Drosophila Dscam1 is a cell-surface protein that plays important roles in neural development and axon tiling of neurons. It is known that thousands of isoforms bind themselves through specific homophilic interactions, a process which provides the basis for cellular self-recognition. Deta...

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Detalhes bibliográficos
Publicado no:BMC Evol Biol
Main Authors: Wang, Guang-Zhong, Marini, Simone, Ma, Xinyun, Yang, Qiang, Zhang, Xuegong, Zhu, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243935/
https://ncbi.nlm.nih.gov/pubmed/25158691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-014-0186-z
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