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Alternative Splicing of Drosophila Dscam Generates Axon Guidance Receptors that Exhibit Isoform-Specific Homophilic Binding

Dscam is an immunoglobulin (Ig) superfamily protein required for the formation of neuronal connections in Drosophila. Through alternative splicing, Dscam potentially gives rise to 19,008 different extracellular domains linked to one of two alternative transmembrane segments, resulting in 38,016 isof...

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Bibliografske podrobnosti
Main Authors: Wojtowicz, Woj M., Flanagan, John J., Millard, S. Sean, Zipursky, S. Lawrence, Clemens, James C.
Format: Artigo
Jezik:Inglês
Izdano: 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691713/
https://ncbi.nlm.nih.gov/pubmed/15339666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2004.08.021
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