Structural basis for PECAM-1 homophilic binding

Platelet endothelial cell adhesion molecule-1 (PECAM-1) is a 130-kDa member of the immunoglobulin gene superfamily (IgSF) that is present on the surface of circulating platelets and leukocytes, and highly expressed at the junctions of confluent endothelial cell monolayers. PECAM-1–mediated homophili...

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Bibliographic Details
Published in:Blood
Main Authors: Paddock, Cathy, Zhou, Dongwen, Lertkiatmongkol, Panida, Newman, Peter J., Zhu, Jieqing
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2016
Subjects:
Vascular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768429/
https://ncbi.nlm.nih.gov/pubmed/26702061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-07-660092
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