Modulation of Curli Assembly and Pellicle Biofilm Formation by Chemical and Protein Chaperones

Enteric bacteria assemble functional amyloid fibers, curli, on their surfaces that share structural and biochemical properties with disease-associated amyloids. Here, we test rationally designed 2-pyridone compounds for their ability to alter amyloid formation of the major curli subunit CsgA. We ide...

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Vydáno v:Chem Biol
Hlavní autoři: Andersson, Emma K., Bengtsson, Christoffer, Evans, Margery L., Chorell, Erik, Sellstedt, Magnus, Lindgren, Anders E.G., Hufnagel, David A., Bhattacharya, Moumita, Tessier, Peter M., Wittung-Stafshede, Pernilla, Almqvist, Fredrik, Chapman, Matthew R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243843/
https://ncbi.nlm.nih.gov/pubmed/24035282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2013.07.017
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