The Bacterial Curli System Possesses a Potent and Selective Inhibitor of Amyloid Formation

Curli are extracellular functional amyloids that are assembled by enteric bacteria during biofilm formation and host colonization. An efficient secretion system and chaperone network ensures that the major curli fiber subunit, CsgA, does not form intracellular amyloid aggregates. We discovered that...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Evans, Margery L., Chorell, Erik, Taylor, Jonathan D., Åden, Jörgen, Göteson, Anna, Li, Fei, Koch, Marion, Sefer, Lea, Matthews, Steve J., Wittung-Stafshede, Pernilla, Almqvist, Fredrik, Chapman, Matthew R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320674/
https://ncbi.nlm.nih.gov/pubmed/25620560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.12.025
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