The Bacterial Curli System Possesses a Potent and Selective Inhibitor of Amyloid Formation

Curli are extracellular functional amyloids that are assembled by enteric bacteria during biofilm formation and host colonization. An efficient secretion system and chaperone network ensures that the major curli fiber subunit, CsgA, does not form intracellular amyloid aggregates. We discovered that...

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Détails bibliographiques
Publié dans:Mol Cell
Auteurs principaux: Evans, Margery L., Chorell, Erik, Taylor, Jonathan D., Åden, Jörgen, Göteson, Anna, Li, Fei, Koch, Marion, Sefer, Lea, Matthews, Steve J., Wittung-Stafshede, Pernilla, Almqvist, Fredrik, Chapman, Matthew R.
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320674/
https://ncbi.nlm.nih.gov/pubmed/25620560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.12.025
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