A noncanonical Frizzled2 pathway regulates epithelial-mesenchymal transition and metastasis

Wnt signaling plays a critical role in embryonic development, and genetic aberrations in this network have been broadly implicated in colorectal cancer. We find that the Wnt receptor Frizzled2 (Fzd2) and its ligands Wnt5a/b are elevated in metastatic liver, lung, colon, and breast cancer cell lines...

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Detaylı Bibliyografya
Yayımlandı:Cell
Asıl Yazarlar: Gujral, Taranjit S., Chan, Marina, Peshkin, Leonid, Sorger, Peter K., Kirschner, Marc W., MacBeath, Gavin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243058/
https://ncbi.nlm.nih.gov/pubmed/25417160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.10.032
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