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Family-wide investigation of PDZ domain-mediated protein–protein interactions implicates β-catenin in maintaining the integrity of tight junctions
β-catenin is a multifunctional protein that plays a critical role in cell–cell contacts and signal transduction. β-catenin has previously been shown to interact with PDZ domain-containing proteins through its C-terminus. Using protein microarrays comprising 206 mouse PDZ domains, we identified 26 PD...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3728706/ https://ncbi.nlm.nih.gov/pubmed/23790492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2013.04.021 |
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