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Family-wide investigation of PDZ domain-mediated protein–protein interactions implicates β-catenin in maintaining the integrity of tight junctions

β-catenin is a multifunctional protein that plays a critical role in cell–cell contacts and signal transduction. β-catenin has previously been shown to interact with PDZ domain-containing proteins through its C-terminus. Using protein microarrays comprising 206 mouse PDZ domains, we identified 26 PD...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gujral, Taranjit S., Karp, Ethan S., Chan, Marina, Chang, Bryan H., MacBeath, Gavin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728706/
https://ncbi.nlm.nih.gov/pubmed/23790492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2013.04.021
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