K-ATP channels in dopamine substantia nigra neurons control bursting and novelty-induced exploration

Phasic activation of the dopamine (DA) midbrain system in response to unexpected reward or novelty is critical for adaptive behavioral strategies. This activation of DA midbrain neurons occurs via a synaptically triggered switch from low-frequency background spiking to transient high-frequency burst...

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Udgivet i:Nat Neurosci
Main Authors: Schiemann, Julia, Schlaudraff, Falk, Klose, Verena, Bingmer, Markus, Seino, Susumu, Magill, Peter J, Zaghloul, Kareem A, Schneider, Gaby, Liss, Birgit, Roeper, Jochen
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242970/
https://ncbi.nlm.nih.gov/pubmed/22902720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3185
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