K-ATP channels in dopamine substantia nigra neurons control bursting and novelty-induced exploration

Phasic activation of the dopamine (DA) midbrain system in response to unexpected reward or novelty is critical for adaptive behavioral strategies. This activation of DA midbrain neurons occurs via a synaptically triggered switch from low-frequency background spiking to transient high-frequency burst...

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Pubblicato in:Nat Neurosci
Autori principali: Schiemann, Julia, Schlaudraff, Falk, Klose, Verena, Bingmer, Markus, Seino, Susumu, Magill, Peter J, Zaghloul, Kareem A, Schneider, Gaby, Liss, Birgit, Roeper, Jochen
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242970/
https://ncbi.nlm.nih.gov/pubmed/22902720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3185
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