Effects of Inflammation on Hippocampus and Substantia Nigra Responses to Novelty in Healthy Human Participants

Humans are naturally inquisitive. This tendency is adaptive, aiding identification of potentially valuable novel outcomes. The dopaminergic substantia nigra (SN) is implicated in the drive to explore novel stimuli and situations. However, infection and inflammation inhibit the motivation to seek out...

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Bibliographic Details
Published in:Neuropsychopharmacology
Main Authors: Harrison, Neil A, Cercignani, Mara, Voon, Valerie, Critchley, Hugo D
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264953/
https://ncbi.nlm.nih.gov/pubmed/25154706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.222
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