K-ATP channels in dopamine substantia nigra neurons control bursting and novelty-induced exploration

Phasic activation of the dopamine (DA) midbrain system in response to unexpected reward or novelty is critical for adaptive behavioral strategies. This activation of DA midbrain neurons occurs via a synaptically triggered switch from low-frequency background spiking to transient high-frequency burst...

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Detalhes bibliográficos
Publicado no:Nat Neurosci
Main Authors: Schiemann, Julia, Schlaudraff, Falk, Klose, Verena, Bingmer, Markus, Seino, Susumu, Magill, Peter J, Zaghloul, Kareem A, Schneider, Gaby, Liss, Birgit, Roeper, Jochen
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242970/
https://ncbi.nlm.nih.gov/pubmed/22902720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3185
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