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Elevated α-synuclein mRNA levels in individual UV-laser-microdissected dopaminergic substantia nigra neurons in idiopathic Parkinson's disease

The presynaptic protein α-synuclein is involved in several neurodegenerative diseases, including Parkinson's disease (PD). In rare familial forms of PD, causal mutations (PARK1) as well as multiplications (PARK4) of the α-synuclein gene have been identified. In sporadic, idiopathic PD, abnormal...

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Detalhes bibliográficos
Main Authors: Gründemann, Jan, Schlaudraff, Falk, Haeckel, Olga, Liss, Birgit
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367701/
https://ncbi.nlm.nih.gov/pubmed/18332041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn084
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