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Capturing distinct KCNQ2 channel resting states by metal ion bridges in the voltage-sensor domain

Although crystal structures of various voltage-gated K(+) (Kv) and Na(+) channels have provided substantial information on the activated conformation of the voltage-sensing domain (VSD), the topology of the VSD in its resting conformation remains highly debated. Numerous studies have investigated th...

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Detalles Bibliográficos
Publicado en:J Gen Physiol
Main Authors: Gourgy-Hacohen, Orit, Kornilov, Polina, Pittel, Ilya, Peretz, Asher, Attali, Bernard, Paas, Yoav
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242811/
https://ncbi.nlm.nih.gov/pubmed/25385787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201411221
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