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Channel gating pore: a new therapeutic target
Each subunit of voltage-gated cation channels comprises a voltage-sensing domain and a pore region. In a paper recently published in Cell Research, Li et al. showed that the gating charge pathway of the voltage sensor of the KCNQ2 K(+) channel can accommodate small opener molecules and offer a new t...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3760620/ https://ncbi.nlm.nih.gov/pubmed/23835478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.89 |
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