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Channel gating pore: a new therapeutic target

Each subunit of voltage-gated cation channels comprises a voltage-sensing domain and a pore region. In a paper recently published in Cell Research, Li et al. showed that the gating charge pathway of the voltage sensor of the KCNQ2 K(+) channel can accommodate small opener molecules and offer a new t...

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Detalhes bibliográficos
Main Authors: Kornilov, Polina, Peretz, Asher, Attali, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760620/
https://ncbi.nlm.nih.gov/pubmed/23835478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.89
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