SN79, a sigma receptor antagonist, attenuates methamphetamine-induced astrogliosis through a blockade of OSMR/gp130 signaling and STAT3 phosphorylation

Methamphetamine (METH) exposure results in dopaminergic neurotoxicity in striatal regions of the brain, an effect that has been linked to an increased risk of Parkinson's disease. Various aspects of neuroinflammation, including astrogliosis, are believed to be contributory factors in METH neuro...

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Xehetasun bibliografikoak
Argitaratua izan da:Exp Neurol
Egile Nagusiak: Robson, Matthew J., Turner, Ryan C., Naser, Zachary J., McCurdy, Christopher R., O'Callaghan, James P., Huber, Jason D., Matsumoto, Rae R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241368/
https://ncbi.nlm.nih.gov/pubmed/24508558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2014.01.020
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