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Uptake of Shiga-toxigenic Escherichia coli SubAB by HeLa cells requires an actin– and lipid raft -dependent pathway
The novel cytotoxic factor Subtilase cytotoxin (SubAB) is produced mainly by non-O157 Shiga-toxigenic Escherichia coli (STEC). SubAB cleaves the molecular chaperone BiP/GRP78 in the endoplasmic reticulum (ER), leading to activation of RNA-dependent protein kinase (PKR)-like ER kinase (PERK), followe...
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| Veröffentlicht in: | Cell Microbiol |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4241268/ https://ncbi.nlm.nih.gov/pubmed/24844382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12315 |
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