Mechanism of inhibition of Shiga-toxigenic Escherichia coli SubAB cytotoxicity by steroids and diacylglycerol analogues

Shiga toxigenic Escherichia coli (STEC) are responsible for a worldwide foodborne disease, which is characterized by severe bloody diarrhea and hemolytic uremic syndrome (HUS). Subtilase cytotoxin (SubAB) is a novel AB(5) toxin, which is produced by Locus for Enterocyte Effacement (LEE)-negative STE...

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Vydáno v:Cell Death Discov
Hlavní autoři: Yahiro, Kinnosuke, Nagasawa, Sayaka, Ichimura, Kimitoshi, Takeuchi, Hiroki, Ogura, Kohei, Tsutsuki, Hiroyasu, Shimizu, Takeshi, Iyoda, Sunao, Ohnishi, Makoto, Iwase, Hirotaro, Moss, Joel, Noda, Masatoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841432/
https://ncbi.nlm.nih.gov/pubmed/29531819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-017-0007-4
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