DAP1, a Negative Regulator of Autophagy, Controls SubAB-Mediated Apoptosis and Autophagy

Autophagy and apoptosis play critical roles in cellular homeostasis and survival. Subtilase cytotoxin (SubAB), produced by non-O157 type Shiga-toxigenic Escherichia coli (STEC), is an important virulence factor in disease. SubAB, a protease, cleaves a specific site on the endoplasmic reticulum (ER)...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Yahiro, Kinnosuke, Tsutsuki, Hiroyasu, Ogura, Kohei, Nagasawa, Sayaka, Moss, Joel, Noda, Masatoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249318/
https://ncbi.nlm.nih.gov/pubmed/25183729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02213-14
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