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Parameter estimation of dynamic biological network models using integrated fluxes

BACKGROUND: Parameter estimation is often the bottlenecking step in biological system modeling. For ordinary differential equation (ODE) models, the challenge in this estimation has been attributed to not only the lack of parameter identifiability, but also computational issues such as finding globa...

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Dades bibliogràfiques
Publicat a:BMC Syst Biol
Autors principals: Liu, Yang, Gunawan, Rudiyanto
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241227/
https://ncbi.nlm.nih.gov/pubmed/25403239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-014-0127-x
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