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Parameter estimation of dynamic biological network models using integrated fluxes

BACKGROUND: Parameter estimation is often the bottlenecking step in biological system modeling. For ordinary differential equation (ODE) models, the challenge in this estimation has been attributed to not only the lack of parameter identifiability, but also computational issues such as finding globa...

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Bibliographic Details
Published in:BMC Syst Biol
Main Authors: Liu, Yang, Gunawan, Rudiyanto
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241227/
https://ncbi.nlm.nih.gov/pubmed/25403239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-014-0127-x
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