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Parameter estimation of dynamic biological network models using integrated fluxes

BACKGROUND: Parameter estimation is often the bottlenecking step in biological system modeling. For ordinary differential equation (ODE) models, the challenge in this estimation has been attributed to not only the lack of parameter identifiability, but also computational issues such as finding globa...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: Liu, Yang, Gunawan, Rudiyanto
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241227/
https://ncbi.nlm.nih.gov/pubmed/25403239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-014-0127-x
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