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Identification of parameter correlations for parameter estimation in dynamic biological models

BACKGROUND: One of the challenging tasks in systems biology is parameter estimation in nonlinear dynamic models. A biological model usually contains a large number of correlated parameters leading to non-identifiability problems. Although many approaches have been developed to address both structura...

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Autori principali: Li, Pu, Vu, Quoc Dong
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015753/
https://ncbi.nlm.nih.gov/pubmed/24053643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-7-91
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