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Treatment Response in the PIVENS Trial is Associated with Decreased Hedgehog Pathway Activity
Hedgehog (Hh) ligand production by ballooned hepatocytes drives nonalcoholic steatohepatitis (NASH) progression in mice. The NIDDK-sponsored PIVENS trial (NCT00063622) showed that Vitamin E (VitE) improved NASH. We investigated whether VitE treatment and improvement in NASH were associated with chan...
Tallennettuna:
| Julkaisussa: | Hepatology |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4241186/ https://ncbi.nlm.nih.gov/pubmed/24849310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27235 |
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