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Increased Production of Sonic Hedgehog by Ballooned Hepatocytes

Ballooned hepatocytes distinguish nonalcoholic steatohepatitis (NASH) from steatosis. Such cells contain dilated endoplasmic reticulum and ubiquitin aggregates, characteristics of endoplasmic reticulum stress. Hepatocyte ballooning increases risk for fibrosis in NASH, suggesting ballooned hepatocyte...

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Detalhes bibliográficos
Main Authors: Rangwala, Fatima, Guy, Cynthia D., Lu, Jiuyi, Suzuki, Ayako, Burchette, James L., Abdelmalek, Manal F., Chen, Wei, Diehl, Anna Mae
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628812/
https://ncbi.nlm.nih.gov/pubmed/21547909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2888
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