Increased Production of Sonic Hedgehog by Ballooned Hepatocytes

Ballooned hepatocytes distinguish nonalcoholic steatohepatitis (NASH) from steatosis. Such cells contain dilated endoplasmic reticulum and ubiquitin aggregates, characteristics of endoplasmic reticulum stress. Hepatocyte ballooning increases risk for fibrosis in NASH, suggesting ballooned hepatocyte...

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Bibliografiske detaljer
Main Authors: Rangwala, Fatima, Guy, Cynthia D., Lu, Jiuyi, Suzuki, Ayako, Burchette, James L., Abdelmalek, Manal F., Chen, Wei, Diehl, Anna Mae
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628812/
https://ncbi.nlm.nih.gov/pubmed/21547909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2888
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