CRF neurons in the ventral tegmental area control the aversive effects of nicotine withdrawal and promote escalation of nicotine intake

Dopaminergic neurons in the ventral tegmental area (VTA) are well known for their role in mediating the positive reinforcing effects of drugs of abuse. Here, we identify in rodents and humans a population of VTA dopamine neurons co-expressing corticotropin releasing factor (CRF). We provide further...

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Foilsithe in:Nat Neurosci
Main Authors: Grieder, Taryn E., Herman, Melissa A., Contet, Candice, Tan, Laura A., Vargas-Perez, Hector, Cohen, Ami, Chwalek, Michal, Maal-Bared, Geith, Freiling, John, Schlosburg, Joel E, Clarke, Laura, Crawford, Elena, Koebel, Pascale, Canonigo, Vez, Sanna, Pietro, Tapper, Andrew, Roberto, Marisa, Kieffer, Brigitte L., Sawchenko, Paul E., Koob, George F., van der Kooy, Derek, George, Olivier
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241147/
https://ncbi.nlm.nih.gov/pubmed/25402857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3872
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