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Recombinant expression, purification, and biophysical characterization of the transmembrane and membrane proximal domains of HIV-1 gp41

The transmembrane subunit (gp41) of the envelope glycoprotein of HIV-1 associates noncovalently with the surface subunit (gp120) and together they play essential roles in viral mucosal transmission and infection of target cells. The membrane proximal region (MPR) of gp41 is highly conserved and cont...

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Библиографические подробности
Опубликовано в: :Protein Sci
Главные авторы: Gong, Zhen, Kessans, Sarah A, Song, Lusheng, Dörner, Katerina, Lee, Ho-Hsien, Meador, Lydia R, LaBaer, Joshua, Hogue, Brenda G, Mor, Tsafrir S, Fromme, Petra
Формат: Artigo
Язык:Inglês
Опубликовано: BlackWell Publishing Ltd 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241111/
https://ncbi.nlm.nih.gov/pubmed/25155369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2540
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