Recombinant expression, purification, and biophysical characterization of the transmembrane and membrane proximal domains of HIV-1 gp41

The transmembrane subunit (gp41) of the envelope glycoprotein of HIV-1 associates noncovalently with the surface subunit (gp120) and together they play essential roles in viral mucosal transmission and infection of target cells. The membrane proximal region (MPR) of gp41 is highly conserved and cont...

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Publicado no:Protein Sci
Main Authors: Gong, Zhen, Kessans, Sarah A, Song, Lusheng, Dörner, Katerina, Lee, Ho-Hsien, Meador, Lydia R, LaBaer, Joshua, Hogue, Brenda G, Mor, Tsafrir S, Fromme, Petra
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241111/
https://ncbi.nlm.nih.gov/pubmed/25155369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2540
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