α2β1 Integrin, GPVI Receptor, and Common FcRγ Chain on Mouse Platelets Mediate Distinct Responses to Collagen in Models of Thrombosis

OBJECTIVE: Platelets express the α2β1 integrin and the glycoprotein VI (GPVI)/FcRγ complex, both collagen receptors. Understanding platelet-collagen receptor function has been enhanced through use of genetically modified mouse models. Previous studies of GPVI/FcRγ-mediated collagen-induced platelet...

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Udgivet i:PLoS One
Main Authors: Marjoram, Robin J., Li, Zhengzhi, He, Li, Tollefsen, Douglas M., Kunicki, Thomas J., Dickeson, S. Kent, Santoro, Samuel A., Zutter, Mary M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240667/
https://ncbi.nlm.nih.gov/pubmed/25415203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114035
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