Heme activates platelets and exacerbates rhabdomyolysis-induced acute kidney injury via CLEC-2 and GPVI/FcRγ

There is increasing evidence that platelets participate in multiple pathophysiological processes other than thrombosis and hemostasis, such as immunity, inflammation, embryonic development, and cancer progression. A recent study revealed that heme (hemin)-activated platelets induce macrophage extrac...

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Bibliografske podrobnosti
izdano v:Blood Adv
Main Authors: Oishi, Saori, Tsukiji, Nagaharu, Otake, Shimon, Oishi, Naoki, Sasaki, Tomoyuki, Shirai, Toshiaki, Yoshikawa, Yuri, Takano, Katsuhiro, Shinmori, Hideyuki, Inukai, Takeshi, Kondo, Tetsuo, Suzuki-Inoue, Katsue
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2021
Teme:
Platelets and Thrombopoiesis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045506/
https://ncbi.nlm.nih.gov/pubmed/33843987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020001698
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