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C-type lectin-like receptor-2 (CLEC-2) is a key regulator of kappa-carrageenan-induced tail thrombosis model in mice

Kappa-carrageenan (KCG), which is used to induce thrombosis in laboratory animals for antithrombotic drug screening, can trigger platelet aggregation. However, the cell-surface receptor and related signaling pathways remain unclear. In this study, we investigated the molecular basis of KCG-induced p...

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Main Authors: Ryohei Yokomori, Toshiaki Shirai, Nagaharu Tsukiji, Saori Oishi, Tomoyuki Sasaki, Katsuhiro Takano, Katsue Suzuki-Inoue
Format: Artigo
Language:Inglês
Published: Taylor & Francis Group 2023-12-01
Series:Platelets
Subjects:
animal model
carrageenan
C-type lectin-like receptor 2 (CLEC-2)
Platelet
polysaccharide
thrombosis
Online Access:https://www.tandfonline.com/doi/10.1080/09537104.2023.2281941
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