TC21/RRas2 regulates GPVI-FcRγ-mediated platelet activation and thrombus stability

BACKGROUND: Many RAS family small GTPases are expressed in platelets, including RAC, RHOA, RAP, and H-/N-/RRAS1, but most of their signaling and cellular functions remain poorly understood. Like RRAS1, TC21/RRAS2 reverses HRAS-induced suppression of integrin activation in CHO cells. However, a role...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Thromb Haemost
Main Authors: Janapati, Sumalaxmi, Wurtzel, Jeremy, Dangelmaier, Carol, Manne, Bhanu Kanth, Bhavanasi, Dheeraj, Kostyak, John C., Kim, Soochong, Holinstat, Michael, Kunapuli, Satya P., Goldfinger, Lawrence E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286703/
https://ncbi.nlm.nih.gov/pubmed/29883056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14197
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados