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Immunotherapy alleviates amyloid-associated synaptic pathology in an Alzheimer’s disease mouse model
Cognitive decline in Alzheimer’s disease is attributed to loss of functional synapses, most likely caused by synaptotoxic, oligomeric forms of amyloid-β. Many treatment options aim at reducing amyloid-β levels in the brain, either by decreasing its production or by increasing its clearance. We quant...
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| Publié dans: | Brain |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4240293/ https://ncbi.nlm.nih.gov/pubmed/25281869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awu280 |
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