Immunotherapy alleviates amyloid-associated synaptic pathology in an Alzheimer’s disease mouse model

Cognitive decline in Alzheimer’s disease is attributed to loss of functional synapses, most likely caused by synaptotoxic, oligomeric forms of amyloid-β. Many treatment options aim at reducing amyloid-β levels in the brain, either by decreasing its production or by increasing its clearance. We quant...

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Bibliographic Details
Published in:Brain
Main Authors: Dorostkar, Mario M., Burgold, Steffen, Filser, Severin, Barghorn, Stefan, Schmidt, Boris, Anumala, Upendra Rao, Hillen, Heinz, Klein, Corinna, Herms, Jochen
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4240293/
https://ncbi.nlm.nih.gov/pubmed/25281869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awu280
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