A carregar...
Exploiting the interaction between Grp94 and aggregated myocilin to treat glaucoma
Gain-of-function mutations in the olfactomedin domain of the MYOC gene facilitate the toxic accumulation of amyloid-containing myocilin aggregates, hastening the onset of the prevalent ocular disorder primary open-angle glaucoma. Aggregation of wild-type myocilin has been reported in other glaucoma...
Na minha lista:
| Publicado no: | Hum Mol Genet |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4240202/ https://ncbi.nlm.nih.gov/pubmed/25027323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu367 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|