Pharmacokinetic tools for the dose adjustment of ciclosporin in haematopoietic stem cell transplant patients

AIMS: Ciclosporin A (CsA) is used in the prophylaxis and treatment of acute and chronic graft vs. host disease after haematopoietic stem cell (HSCT) transplantation. Our objective was to build and compare three independent Bayesian estimators of CsA area under the curve (AUC) using a limited samplin...

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Detalles Bibliográficos
Publicado en:Br J Clin Pharmacol
Autores principales: Woillard, Jean-Baptiste, Lebreton, Vincent, Neely, Michael, Turlure, Pascal, Girault, Stéphane, Debord, Jean, Marquet, Pierre, Saint-Marcoux, Franck
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2014
Materias:
Pharmacokinetics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239977/
https://ncbi.nlm.nih.gov/pubmed/24698009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12394
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