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Pharmacokinetic tools for the dose adjustment of ciclosporin in haematopoietic stem cell transplant patients

AIMS: Ciclosporin A (CsA) is used in the prophylaxis and treatment of acute and chronic graft vs. host disease after haematopoietic stem cell (HSCT) transplantation. Our objective was to build and compare three independent Bayesian estimators of CsA area under the curve (AUC) using a limited samplin...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Woillard, Jean-Baptiste, Lebreton, Vincent, Neely, Michael, Turlure, Pascal, Girault, Stéphane, Debord, Jean, Marquet, Pierre, Saint-Marcoux, Franck
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239977/
https://ncbi.nlm.nih.gov/pubmed/24698009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12394
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