Pharmacokinetic tools for the dose adjustment of ciclosporin in haematopoietic stem cell transplant patients

AIMS: Ciclosporin A (CsA) is used in the prophylaxis and treatment of acute and chronic graft vs. host disease after haematopoietic stem cell (HSCT) transplantation. Our objective was to build and compare three independent Bayesian estimators of CsA area under the curve (AUC) using a limited samplin...

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Bibliographic Details
Published in:Br J Clin Pharmacol
Main Authors: Woillard, Jean-Baptiste, Lebreton, Vincent, Neely, Michael, Turlure, Pascal, Girault, Stéphane, Debord, Jean, Marquet, Pierre, Saint-Marcoux, Franck
Format: Artigo
Language:Inglês
Published: BlackWell Publishing Ltd 2014
Subjects:
Pharmacokinetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239977/
https://ncbi.nlm.nih.gov/pubmed/24698009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12394
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