Pharmacokinetics of mycophenolate mofetil in children with lupus and clinical findings in favour of therapeutic drug monitoring

AIMS: The use of mycophenolate mofetil (MMF) in children with systemic lupus erythematosus (SLE) is increasing. However, the clinical benefit of its monitoring has been scarcely studied, and little is known about its pharmacokinetics in this context. The objectives of the present study were: (i) to...

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Dettagli Bibliografici
Pubblicato in:Br J Clin Pharmacol
Autori principali: Woillard, Jean-Baptiste, Bader-Meunier, Brigitte, Salomon, Rémi, Ranchin, Bruno, Decramer, Stéphane, Fischbach, Michel, Berard, Etienne, Guigonis, Vincent, Harambat, Jérôme, Dunand, Olivier, Tenenbaum, Julie, Marquet, Pierre, Saint-Marcoux, Franck
Natura: Artigo
Lingua:Inglês
Pubblicazione: BlackWell Publishing Ltd 2014
Soggetti:
Pharmacokinetic Dynamic Relationships
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239980/
https://ncbi.nlm.nih.gov/pubmed/24697955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12392
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