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Pharmacokinetics of mycophenolate mofetil in children with lupus and clinical findings in favour of therapeutic drug monitoring

AIMS: The use of mycophenolate mofetil (MMF) in children with systemic lupus erythematosus (SLE) is increasing. However, the clinical benefit of its monitoring has been scarcely studied, and little is known about its pharmacokinetics in this context. The objectives of the present study were: (i) to...

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Bibliographic Details
Published in:Br J Clin Pharmacol
Main Authors: Woillard, Jean-Baptiste, Bader-Meunier, Brigitte, Salomon, Rémi, Ranchin, Bruno, Decramer, Stéphane, Fischbach, Michel, Berard, Etienne, Guigonis, Vincent, Harambat, Jérôme, Dunand, Olivier, Tenenbaum, Julie, Marquet, Pierre, Saint-Marcoux, Franck
Format: Artigo
Language:Inglês
Published: BlackWell Publishing Ltd 2014
Subjects:
Pharmacokinetic Dynamic Relationships
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239980/
https://ncbi.nlm.nih.gov/pubmed/24697955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12392
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