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Pharmacokinetic tools for the dose adjustment of ciclosporin in haematopoietic stem cell transplant patients

AIMS: Ciclosporin A (CsA) is used in the prophylaxis and treatment of acute and chronic graft vs. host disease after haematopoietic stem cell (HSCT) transplantation. Our objective was to build and compare three independent Bayesian estimators of CsA area under the curve (AUC) using a limited samplin...

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Vydáno v:Br J Clin Pharmacol
Hlavní autoři: Woillard, Jean-Baptiste, Lebreton, Vincent, Neely, Michael, Turlure, Pascal, Girault, Stéphane, Debord, Jean, Marquet, Pierre, Saint-Marcoux, Franck
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239977/
https://ncbi.nlm.nih.gov/pubmed/24698009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12394
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