Preservation of Memory With Conformal Avoidance of the Hippocampal Neural Stem-Cell Compartment During Whole-Brain Radiotherapy for Brain Metastases (RTOG 0933): A Phase II Multi-Institutional Trial

PURPOSE: Hippocampal neural stem-cell injury during whole-brain radiotherapy (WBRT) may play a role in memory decline. Intensity-modulated radiotherapy can be used to avoid conformally the hippocampal neural stem-cell compartment during WBRT (HA-WBRT). RTOG 0933 was a single-arm phase II study of HA...

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Publicado en:J Clin Oncol
Autores principales: Gondi, Vinai, Pugh, Stephanie L., Tome, Wolfgang A., Caine, Chip, Corn, Ben, Kanner, Andrew, Rowley, Howard, Kundapur, Vijayananda, DeNittis, Albert, Greenspoon, Jeffrey N., Konski, Andre A., Bauman, Glenn S., Shah, Sunjay, Shi, Wenyin, Wendland, Merideth, Kachnic, Lisa, Mehta, Minesh P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Clinical Oncology 2014
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ORIGINAL REPORTS
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239303/
https://ncbi.nlm.nih.gov/pubmed/25349290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2014.57.2909
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