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DNA methylation of a GC repressor element in the SM MHC promoter facilitates binding of the Notch-associated transcription factor, RBPJ/CSL1
OBJECTIVE: The goal of the present study was to identify novel mechanisms that regulate SMC differentiation marker gene expression. APPROACH AND RESULTS: We demonstrate that the CArG-containing regions of many SMC-specific promoters are imbedded within CpG islands. A previously identified GC repress...
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| Publicado en: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4239181/ https://ncbi.nlm.nih.gov/pubmed/25324571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.304634 |
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