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DNA methylation of a GC repressor element in the SM MHC promoter facilitates binding of the Notch-associated transcription factor, RBPJ/CSL1

OBJECTIVE: The goal of the present study was to identify novel mechanisms that regulate SMC differentiation marker gene expression. APPROACH AND RESULTS: We demonstrate that the CArG-containing regions of many SMC-specific promoters are imbedded within CpG islands. A previously identified GC repress...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Arterioscler Thromb Vasc Biol
Prif Awduron: Rozenberg, Julian M., Tesfu, Daniel B., Musunuri, Srilaxmi, Taylor, Joan M., Mack, Christopher P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239181/
https://ncbi.nlm.nih.gov/pubmed/25324571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.304634
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