Hemoglobin α / eNOS Coupling at Myoendothelial Junctions is Required for Nitric Oxide Scavenging During Vasoconstriction

OBJECTIVE: Hb α and eNOS form a macromolecular complex at myoendothelial junctions; the functional role of this interaction remains undefined. To test if coupling of eNOS and Hb α regulates NO signaling, vascular reactivity and blood pressure using a mimetic peptide of Hb α to disrupt this interacti...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Arterioscler Thromb Vasc Biol
Autori principali: Straub, Adam C., Butcher, Joshua T., Billaud, Marie, Mutchler, Stephanie M., Artamonov, Mykhaylo V., Nguyen, Anh T., Johnson, Tyler, Best, Angela K., Miller, Megan P., Palmer, Lisa A., Columbus, Linda, Somlyo, Avril V., Le, Thu H., Isakson, Brant E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239174/
https://ncbi.nlm.nih.gov/pubmed/25278292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.303974
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi