Hemoglobin α / eNOS Coupling at Myoendothelial Junctions is Required for Nitric Oxide Scavenging During Vasoconstriction

OBJECTIVE: Hb α and eNOS form a macromolecular complex at myoendothelial junctions; the functional role of this interaction remains undefined. To test if coupling of eNOS and Hb α regulates NO signaling, vascular reactivity and blood pressure using a mimetic peptide of Hb α to disrupt this interacti...

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Bibliografiska uppgifter
I publikationen:Arterioscler Thromb Vasc Biol
Huvudupphovsmän: Straub, Adam C., Butcher, Joshua T., Billaud, Marie, Mutchler, Stephanie M., Artamonov, Mykhaylo V., Nguyen, Anh T., Johnson, Tyler, Best, Angela K., Miller, Megan P., Palmer, Lisa A., Columbus, Linda, Somlyo, Avril V., Le, Thu H., Isakson, Brant E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239174/
https://ncbi.nlm.nih.gov/pubmed/25278292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.303974
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